Reproductive & Hormonal

Tymlos (brand, US), Eladynos (brand, EU/GB), BA058, BIM-44058, PTHrP(1-34) analog

A synthetic 34-amino-acid analog of parathyroid hormone-related protein (PTHrP 1-34) and an approved osteoanabolic (bone-forming) medicine for osteoporosis, marketed as Tymlos (US) and Eladynos (EU/UK). Approved medicine — the approval applies to the specific licensed products, not to research-grade material.

GnRH (gonadotropin-releasing hormone), LHRH (luteinizing hormone-releasing hormone), Factrel (brand, diagnostic), Lutrepulse / Lutropulse (brand, fertility), Relefact / HRF / Luforan (brands)

Gonadorelin is synthetic gonadotropin-releasing hormone (GnRH/LHRH), the natural decapeptide that drives the reproductive axis. Given in pulses it stimulates the pituitary to release LH and FSH; given continuously it paradoxically suppresses them. It has a genuine human approval history (Factrel for diagnostic testing; Lutrepulse for hypothalamic-amenorrhoea infertility), but those products are discontinued in the US, and it remains widely used in veterinary medicine.

Metastin, KISS1-derived peptide, Kisspeptin-54, Kisspeptin-13, Kisspeptin-10

A family of neuropeptides encoded by the KISS1 gene (originally identified as the metastasis suppressor "metastin") that act through the KISS1R/GPR54 receptor as a master upstream regulator of the reproductive axis, stimulating GnRH and thereby LH and FSH.

Pitocin (brand), Syntocinon (brand), OT, OXT

An endogenous nonapeptide hormone made in the hypothalamus and released by the posterior pituitary. Synthetic oxytocin (Pitocin, Syntocinon) is an FDA- and EU-approved obstetric medicine for labor induction/augmentation and control of postpartum bleeding; its widely publicized roles in social bonding, trust and autism are an active but mixed and investigational research area.

KEDP, Lys-Glu-Asp-Pro, H-Lys-Glu-Asp-Pro-OH, Prostate peptide bioregulator, Khavinson prostate peptide

A synthetic short-chain tetrapeptide (Lys-Glu-Asp-Pro, KEDP) of the Khavinson "peptide bioregulator" class, marketed as a "prostate bioregulator." Its chemistry is well defined in PubChem, but its published evidence is a small, older, mostly-Russian body of in-vitro chromatin/gerontology work — not prostate clinical trials. Not approved by the FDA or EMA; supplied in the West only as a research reagent.

Bremelanotide, Vyleesi (brand), PT-141, PT 141

A synthetic cyclic-peptide analog of alpha-melanocyte-stimulating hormone that acts as a melanocortin receptor agonist (notably MC4R). Marketed as Vyleesi, it is FDA-approved (2019) for acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women, given as an as-needed subcutaneous injection.

PTH(1-34), rhPTH(1-34), recombinant human parathyroid hormone (1-34), Forteo, Forsteo, Bonsity, parathyroid hormone fragment 1-34

Recombinant human parathyroid hormone fragment PTH(1-34), the first anabolic (bone-forming) osteoporosis medicine and a PTH1 receptor agonist. FDA-approved November 2002 (Forteo/Forsteo; EMA June 2003; follow-on Bonsity 2019).

KEDG, Lys-Glu-Asp-Gly, H-Lys-Glu-Asp-Gly-OH, lysyl-glutamyl-aspartyl-glycine

A synthetic tetrapeptide (Lys-Glu-Asp-Gly, "KEDG") from Vladimir Khavinson's "short peptide bioregulator" school, marketed toward testicular/testosterone and thyroid "support." The honest evidence is thin, older, and mostly Russian — the actual PubMed-indexed primary work is thyroid biology in hypophysectomised birds plus in-vitro DNA-binding data, with no published human clinical trials. Not approved for human use.