Reproductive & Hormonal
Cetrorelix
Cetrotide; cetrorelix acetate
1 min read · Updated July 27, 2026 · 3 references
Curated by PeptideInfo Wikilast reviewed how we verify
An approved GnRH antagonist used during controlled ovarian stimulation to prevent a premature LH surge and ovulation.
Evidence: Regulator-approved drug with human trial evidence.
Approved in: FDA (United States; controlled ovarian stimulation)
- An approved GnRH antagonist used during controlled ovarian stimulation to prevent a premature LH surge and ovulation.
- It competitively blocks pituitary GnRH receptors; suppression is rapid and reversible, without the initial agonist flare.
- Hypersensitivity, including rare severe reactions, can occur. Treatment belongs in a monitored fertility protocol because ovarian response and OHSS risk determine the wider regimen.
An approved GnRH antagonist used during controlled ovarian stimulation to prevent a premature LH surge and ovulation.
Overview
An approved GnRH antagonist used during controlled ovarian stimulation to prevent a premature LH surge and ovulation.
Primary regulatory source
This is an educational reference, not individual medical advice. Use requires a prescriber and indication-specific monitoring.
Identity and mechanism
It competitively blocks pituitary GnRH receptors; suppression is rapid and reversible, without the initial agonist flare.
PubChem CID 25074887; C70H92ClN17O14; 1431.0 Da.
Regulatory label facts
FDA (United States; controlled ovarian stimulation).
The dose below reproduces a regulator-approved label; it is not a treatment recommendation. Cetrotide: 0.25 mg subcutaneously once daily from stimulation day 5 or 6 through the day of hCG administration, under specialist monitoring.
Safety boundary
Hypersensitivity, including rare severe reactions, can occur. Treatment belongs in a monitored fertility protocol because ovarian response and OHSS risk determine the wider regimen.
This is an educational reference, not individual medical advice. Use requires a prescriber and indication-specific monitoring.
References
Frequently asked questions
- What is Cetrorelix?
- An approved GnRH antagonist used during controlled ovarian stimulation to prevent a premature LH surge and ovulation.
- Is Cetrorelix approved as a medicine, and where?
- It is an approved prescription medicine, but where it is approved matters: FDA (United States; controlled ovarian stimulation). It should only be used under medical supervision.
- What is Cetrorelix studied for?
- Cetrorelix is most often discussed in the context of approved peptide medicines — verification pilot. Being studied for an area does not mean it is proven or approved for it.
- Does Cetrorelix have human clinical trials?
- Yes. Cetrorelix has been studied in human clinical trials and is an approved medicine in at least some regions.
Educational disclaimer. This article summarizes published research for informational purposes and is not medical advice. Cetrorelix is an approved medicine within the stated approval scope (FDA (United States; controlled ovarian stimulation)) and must only be used under medical supervision; research-grade or unprescribed material is not a lawful substitute. Consult a qualified healthcare professional before making health decisions.